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Sinemet® Shortage

close up of sinemet parkinson's disease medication shortage
Posted on: 28 February 2019

The world-wide shortage of all forms of Sinemet® has been ongoing for some time.

We can now confirm that Sinemet® will continue to be in short supply until further notice. The shortage is due to a problem at the manufacturer’s level.

Sinemet® 100/25 is completely out of stock however Kinson 100/25 (generic form of Sinemet®) remains available.

The pharmaceutical company which markets Sinemet® in Australia (Merck, Sharp & Dohme) is keeping prescribing doctors informed of the situation and is encouraging them to switch patients to the alternative brand of levodopa (Madopar®). NB This can only be done by a Dr.

An alternative to changing to Madopar® may be possible: an agreement with Therapeutic Goods Act (TGA) allows pharmacists to access an alternative brand of Sinemet® not previously available in Australia. The pharmacist should contact Medsurge Healthcare: to investigate the availability of controlled release (CR) 200/50 and Immediate Release 250/25. NB This can only be done by a pharmacist.

Merck, Sharp & Dohme are keeping all Doctors, Pharmacists and Parkinson’s Australia informed of the situation.

We advise that if you are experiencing difficulties obtaining supplies of Sinemet® then contact your pharmacy with the above information or contact your prescribing doctor.

We will keep you updated as new information becomes available.